Botulinum toxin is a neurotoxin that helps relax an overly tense muscle by blocking the release of certain chemical substances at the nerve-muscle junction. It is also thought to interfere with the release of pain signals and this principle underlies its effect on migraine. These characteristics of the toxin have been utilised by specialised neurology centres around the world, benefitting hundreds of patients each day.
Depending upon the clinical condition, the toxin is administered by a local injection just under the skin or into the muscle. The procedure may require the guidance of electromyography. The procedure, although associated with mild discomfort, is generally well tolerated. An initial detailed appointment is necessary to ensure the suitability of treatment to the clinical condition. The follow up appointments are short, approximately 20 minutes. The maximum effect of therapy occurs after a few days and repeat injections are needed on periodic basis (generally 3 monthly but the interval may vary depending on your condition and an individual response).